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Biomaterial-based scaffold for in situ chemo-immunotherapy to treat poorly immunogenic tumors
Poorly immunogenic tumors, including triple negative breast cancers (TNBCs), remain resistant to current immunotherapies, due in part to the difficulty of reprogramming the highly immunosuppressive tumor microenvironment (TME). Here we show that peritumorally injected, macroporous alginate gels load...
Autores principales: | Wang, Hua, Najibi, Alexander J., Sobral, Miguel C., Seo, Bo Ri, Lee, Jun Yong, Wu, David, Li, Aileen Weiwei, Verbeke, Catia S., Mooney, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655953/ https://www.ncbi.nlm.nih.gov/pubmed/33173046 http://dx.doi.org/10.1038/s41467-020-19540-z |
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