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Biomaterial-based scaffold for in situ chemo-immunotherapy to treat poorly immunogenic tumors

Poorly immunogenic tumors, including triple negative breast cancers (TNBCs), remain resistant to current immunotherapies, due in part to the difficulty of reprogramming the highly immunosuppressive tumor microenvironment (TME). Here we show that peritumorally injected, macroporous alginate gels load...

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Detalles Bibliográficos
Autores principales: Wang, Hua, Najibi, Alexander J., Sobral, Miguel C., Seo, Bo Ri, Lee, Jun Yong, Wu, David, Li, Aileen Weiwei, Verbeke, Catia S., Mooney, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655953/
https://www.ncbi.nlm.nih.gov/pubmed/33173046
http://dx.doi.org/10.1038/s41467-020-19540-z

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