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Pulmonary surfactant inhibition of nanoparticle uptake by alveolar epithelial cells

Pulmonary surfactant forms a sub-micrometer thick fluid layer that covers the surface of alveolar lumen and inhaled nanoparticles therefore come in to contact with surfactant prior to any interaction with epithelial cells. We investigate the role of the surfactant as a protective physical barrier by...

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Detalles Bibliográficos
Autores principales: Radiom, M., Sarkis, M., Brookes, O., Oikonomou, E. K., Baeza-Squiban, A., Berret, J.-F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655959/
https://www.ncbi.nlm.nih.gov/pubmed/33173147
http://dx.doi.org/10.1038/s41598-020-76332-7