Systems Biology Approaches for Therapeutics Development Against COVID-19

Understanding the systems biology approaches for promoting the development of new therapeutic drugs is attaining importance nowadays. The threat of COVID-19 outbreak needs to be vanished for global welfare, and every section of research is focusing on it. There is an opportunity for finding new, qui...

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Autores principales: Jaiswal, Shweta, Kumar, Mohit, Mandeep, Sunita, Singh, Yogendra, Shukla, Pratyoosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655984/
https://www.ncbi.nlm.nih.gov/pubmed/33194800
http://dx.doi.org/10.3389/fcimb.2020.560240
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author Jaiswal, Shweta
Kumar, Mohit
Mandeep,
Sunita,
Singh, Yogendra
Shukla, Pratyoosh
author_facet Jaiswal, Shweta
Kumar, Mohit
Mandeep,
Sunita,
Singh, Yogendra
Shukla, Pratyoosh
author_sort Jaiswal, Shweta
collection PubMed
description Understanding the systems biology approaches for promoting the development of new therapeutic drugs is attaining importance nowadays. The threat of COVID-19 outbreak needs to be vanished for global welfare, and every section of research is focusing on it. There is an opportunity for finding new, quick, and accurate tools for developing treatment options, including the vaccine against COVID-19. The review at this moment covers various aspects of pathogenesis and host factors for exploring the virus target and developing suitable therapeutic solutions through systems biology tools. Furthermore, this review also covers the extensive details of multiomics tools i.e., transcriptomics, proteomics, genomics, lipidomics, immunomics, and in silico computational modeling aiming towards the study of host–virus interactions in search of therapeutic targets against the COVID-19.
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spelling pubmed-76559842020-11-13 Systems Biology Approaches for Therapeutics Development Against COVID-19 Jaiswal, Shweta Kumar, Mohit Mandeep, Sunita, Singh, Yogendra Shukla, Pratyoosh Front Cell Infect Microbiol Cellular and Infection Microbiology Understanding the systems biology approaches for promoting the development of new therapeutic drugs is attaining importance nowadays. The threat of COVID-19 outbreak needs to be vanished for global welfare, and every section of research is focusing on it. There is an opportunity for finding new, quick, and accurate tools for developing treatment options, including the vaccine against COVID-19. The review at this moment covers various aspects of pathogenesis and host factors for exploring the virus target and developing suitable therapeutic solutions through systems biology tools. Furthermore, this review also covers the extensive details of multiomics tools i.e., transcriptomics, proteomics, genomics, lipidomics, immunomics, and in silico computational modeling aiming towards the study of host–virus interactions in search of therapeutic targets against the COVID-19. Frontiers Media S.A. 2020-10-28 /pmc/articles/PMC7655984/ /pubmed/33194800 http://dx.doi.org/10.3389/fcimb.2020.560240 Text en Copyright © 2020 Jaiswal, Kumar, Mandeep, Sunita, Singh and Shukla http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cellular and Infection Microbiology
Jaiswal, Shweta
Kumar, Mohit
Mandeep,
Sunita,
Singh, Yogendra
Shukla, Pratyoosh
Systems Biology Approaches for Therapeutics Development Against COVID-19
title Systems Biology Approaches for Therapeutics Development Against COVID-19
title_full Systems Biology Approaches for Therapeutics Development Against COVID-19
title_fullStr Systems Biology Approaches for Therapeutics Development Against COVID-19
title_full_unstemmed Systems Biology Approaches for Therapeutics Development Against COVID-19
title_short Systems Biology Approaches for Therapeutics Development Against COVID-19
title_sort systems biology approaches for therapeutics development against covid-19
topic Cellular and Infection Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655984/
https://www.ncbi.nlm.nih.gov/pubmed/33194800
http://dx.doi.org/10.3389/fcimb.2020.560240
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