Dsg2 Upregulation as a Rescue Mechanism in Pemphigus

In pemphigus vulgaris (PV), autoantibodies directed against the desmosomal cadherin desmoglein (Dsg) 3 cause loss of intercellular adhesion. It is known that Dsg3 interactions are directly inhibited by autoantibody binding and that Dsg2 is upregulated in epidermis of PV patients. Here, we investigat...

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Detalles Bibliográficos
Autores principales: Sigmund, Anna M., Steinert, Letyfee S., Egu, Desalegn T., Bayerbach, Franziska C., Waschke, Jens, Vielmuth, Franziska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655986/
https://www.ncbi.nlm.nih.gov/pubmed/33193387
http://dx.doi.org/10.3389/fimmu.2020.581370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655986/
https://www.ncbi.nlm.nih.gov/pubmed/33193387
http://dx.doi.org/10.3389/fimmu.2020.581370

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