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全反式维甲酸调控内质网应激诱导FLT3-ITD蛋白自噬降解促进白血病细胞凋亡
OBJECTIVE: Endoplasmic reticulum stress（ERS）was used as the research emphasis to further investigate the mechanisms of apoptosis of FLT3-ITD-mutated leukemia cells and decreased expression of FLT3-ITD mutated protein induced by all-trans retinoic acid（ATRA）. METHODS: FLT3-ITD-mutated leukemia cell l...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
Editorial office of Chinese Journal of Hematology
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656071/ https://www.ncbi.nlm.nih.gov/pubmed/33190441 http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2020.10.008 |