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7-dehydrocholesterol suppresses melanoma cell proliferation and invasion via Akt1/NF-κB signaling

Melanoma is the most lethal cutaneous cancer with a high metastatic rate worldwide, causing ~55,500 deaths annually. Although the selective B-Raf oncogene serine/threonine-kinase (BRAF) inhibitors, dabrafenib and vemurafenib, have been approved for the treatment of BRAF-mutant metastatic melanoma, t...

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Detalles Bibliográficos
Autores principales: Liu, Jia, Zhong, Feiliang, Cao, Lei, Zhu, Ruiying, Qu, Junze, Yang, Lin, Chen, Tingting, Hu, Yunlong, Wang, Ying, Yao, Mingdong, Xiao, Wenhai, Li, Chun, Li, Bo, Yuan, Yingjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656107/
https://www.ncbi.nlm.nih.gov/pubmed/33193858
http://dx.doi.org/10.3892/ol.2020.12261

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