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First patient management of COVID-19 in Changsha, China: a case report

BACKGROUND: In December 2019, the novel coronavirus disease 2019 (COVID-19) emerged in Wuhan, Hubei Province, China. It rapidly spread and many cases were identified in multiple countries, posing a global health problem. Here, we report the first patient cured of COVID-19 infection in Changsha, Chin...

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Autores principales: Zhou, Jian, Cao, Ziqin, Wang, Wanchun, Huang, Kang, Zheng, Fang, Xie, Yuanlin, Jiang, Dixuan, Zhou, Zhiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656198/
https://www.ncbi.nlm.nih.gov/pubmed/33176693
http://dx.doi.org/10.1186/s12879-020-05545-y
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author Zhou, Jian
Cao, Ziqin
Wang, Wanchun
Huang, Kang
Zheng, Fang
Xie, Yuanlin
Jiang, Dixuan
Zhou, Zhiguo
author_facet Zhou, Jian
Cao, Ziqin
Wang, Wanchun
Huang, Kang
Zheng, Fang
Xie, Yuanlin
Jiang, Dixuan
Zhou, Zhiguo
author_sort Zhou, Jian
collection PubMed
description BACKGROUND: In December 2019, the novel coronavirus disease 2019 (COVID-19) emerged in Wuhan, Hubei Province, China. It rapidly spread and many cases were identified in multiple countries, posing a global health problem. Here, we report the first patient cured of COVID-19 infection in Changsha, China, and the symptoms, diagnosis, treatment, and management of this patient are all described in this report. CASE PRESENTATION: A 57-year-old woman developed cough and fever after returning to Changsha from Wuhan on January 9, 2020. She tested positive for COVID-19 infection, a diagnosis which was supported by chest CT. The patient was treated with lopinavir and ritonavir tablets and interferon alfa-2b injection. A low dose of glucocorticoids was used for a short period to control bilateral lung immune response, and this patient avoided being crushed by cytokine storms that might have occurred. The clinical condition of this patient improved, and a COVID-19 assay conducted on January 25, 2020 generated negative results. This patient recovered and was discharged on January 30, 2020. CONCLUSIONS: Currently, there are numerous reports on COVID-19 infections focusing on the disease’s epidemiological and clinical characteristics. This case describes the symptoms, diagnosis, treatment, and management of a patient cured of COVID-19 infection, which may serve as reference for future cases, while further studies are needed.
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spelling pubmed-76561982020-11-12 First patient management of COVID-19 in Changsha, China: a case report Zhou, Jian Cao, Ziqin Wang, Wanchun Huang, Kang Zheng, Fang Xie, Yuanlin Jiang, Dixuan Zhou, Zhiguo BMC Infect Dis Case Report BACKGROUND: In December 2019, the novel coronavirus disease 2019 (COVID-19) emerged in Wuhan, Hubei Province, China. It rapidly spread and many cases were identified in multiple countries, posing a global health problem. Here, we report the first patient cured of COVID-19 infection in Changsha, China, and the symptoms, diagnosis, treatment, and management of this patient are all described in this report. CASE PRESENTATION: A 57-year-old woman developed cough and fever after returning to Changsha from Wuhan on January 9, 2020. She tested positive for COVID-19 infection, a diagnosis which was supported by chest CT. The patient was treated with lopinavir and ritonavir tablets and interferon alfa-2b injection. A low dose of glucocorticoids was used for a short period to control bilateral lung immune response, and this patient avoided being crushed by cytokine storms that might have occurred. The clinical condition of this patient improved, and a COVID-19 assay conducted on January 25, 2020 generated negative results. This patient recovered and was discharged on January 30, 2020. CONCLUSIONS: Currently, there are numerous reports on COVID-19 infections focusing on the disease’s epidemiological and clinical characteristics. This case describes the symptoms, diagnosis, treatment, and management of a patient cured of COVID-19 infection, which may serve as reference for future cases, while further studies are needed. BioMed Central 2020-11-11 /pmc/articles/PMC7656198/ /pubmed/33176693 http://dx.doi.org/10.1186/s12879-020-05545-y Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Zhou, Jian
Cao, Ziqin
Wang, Wanchun
Huang, Kang
Zheng, Fang
Xie, Yuanlin
Jiang, Dixuan
Zhou, Zhiguo
First patient management of COVID-19 in Changsha, China: a case report
title First patient management of COVID-19 in Changsha, China: a case report
title_full First patient management of COVID-19 in Changsha, China: a case report
title_fullStr First patient management of COVID-19 in Changsha, China: a case report
title_full_unstemmed First patient management of COVID-19 in Changsha, China: a case report
title_short First patient management of COVID-19 in Changsha, China: a case report
title_sort first patient management of covid-19 in changsha, china: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656198/
https://www.ncbi.nlm.nih.gov/pubmed/33176693
http://dx.doi.org/10.1186/s12879-020-05545-y
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