Focus on gastroesophageal reflux disease in patients with cystic fibrosis

Gastroesophageal reflux disease (GERD) is a common gastrointestinal disorder in cystic fibrosis (CF), and based on various studies, its prevalence is elevated since childhood. There are several pathogenetic mechanisms on the basis of association between CF and GERD. However, there are no specific gu...

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Detalles Bibliográficos
Autores principales: Bongiovanni, Annarita, Manti, Sara, Parisi, Giuseppe Fabio, Papale, Maria, Mulè, Enza, Rotolo, Novella, Leonardi, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Minireviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656210/
https://www.ncbi.nlm.nih.gov/pubmed/33244195
http://dx.doi.org/10.3748/wjg.v26.i41.6322
Descripción
Sumario:Gastroesophageal reflux disease (GERD) is a common gastrointestinal disorder in cystic fibrosis (CF), and based on various studies, its prevalence is elevated since childhood. There are several pathogenetic mechanisms on the basis of association between CF and GERD. However, there are no specific guidelines for GERD in CF patients, so diagnosis is based on guidelines performed on patients not affected by CF. The aim of this review is to provide the pathophysiology, diagnostic and therapeutic options, complications, and future directions in the management of GERD patients with CF.

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