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Novel domain expansion methods to improve the computational efficiency of the Chemical Master Equation solution for large biological networks

BACKGROUND: Numerical solutions of the chemical master equation (CME) are important for understanding the stochasticity of biochemical systems. However, solving CMEs is a formidable task. This task is complicated due to the nonlinear nature of the reactions and the size of the networks which result...

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Detalles Bibliográficos
Autores principales:	Kosarwal, Rahul, Kulasiri, Don, Samarasinghe, Sandhya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656229/ https://www.ncbi.nlm.nih.gov/pubmed/33176690 http://dx.doi.org/10.1186/s12859-020-03668-2

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