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Recovery of motor function of chronic spinal cord injury by extracellular pyruvate kinase isoform M2 and the underlying mechanism

In our previous study, we found that pyruvate kinase isoform M2 (PKM2) was secreted from the skeletal muscle and extended axons in the cultured neuron. Indirect evidence suggested that secreted PKM2 might relate to the recovery of motor function in spinal cord injured (SCI) mice. However, in vivo di...

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Detalles Bibliográficos
Autores principales: Kikuchi, Takahiro, Tohda, Chihiro, Suyama, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656253/
https://www.ncbi.nlm.nih.gov/pubmed/33173148
http://dx.doi.org/10.1038/s41598-020-76629-7