WNT/β-catenin pathway activation via Wnt1 overexpression and Axin1 downregulation correlates with cadherin-catenin complex disruption and increased lymph node involvement in micropapillary-predominant lung adenocarcinoma

BACKGROUND: Micropapillary-predominant adenocarcinoma (MPA) of the lung is associated with extensive lymph node involvement and rapid terminal metastasis. However, this subtype has been recognized for only a few years, and there have been few studies of the molecular mechanisms associated with its h...

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Detalles Bibliográficos
Autores principales: Zhu, Liang, Yang, Shifeng, Zheng, Linfeng, Zhang, Gu, Cheng, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656375/
https://www.ncbi.nlm.nih.gov/pubmed/33209423
http://dx.doi.org/10.21037/jtd-20-1495

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