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Engineered trimeric ACE2 binds viral spike protein and locks it in “Three-up” conformation to potently inhibit SARS-CoV-2 infection
| Autores principales: | , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Singapore
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656503/ https://www.ncbi.nlm.nih.gov/pubmed/33177651 http://dx.doi.org/10.1038/s41422-020-00438-w |
| _version_ | 1783608392790573056 |
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| author | Guo, Liang Bi, Wenwen Wang, Xinling Xu, Wei Yan, Renhong Zhang, Yuanyuan Zhao, Kai Li, Yaning Zhang, Mingfeng Cai, Xia Jiang, Shibo Xie, Youhua Zhou, Qiang Lu, Lu Dang, Bobo |
| author_facet | Guo, Liang Bi, Wenwen Wang, Xinling Xu, Wei Yan, Renhong Zhang, Yuanyuan Zhao, Kai Li, Yaning Zhang, Mingfeng Cai, Xia Jiang, Shibo Xie, Youhua Zhou, Qiang Lu, Lu Dang, Bobo |
| author_sort | Guo, Liang |
| collection | PubMed |
| description | |
| format | Online Article Text |
| id | pubmed-7656503 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | Springer Singapore |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-76565032020-11-12 Engineered trimeric ACE2 binds viral spike protein and locks it in “Three-up” conformation to potently inhibit SARS-CoV-2 infection Guo, Liang Bi, Wenwen Wang, Xinling Xu, Wei Yan, Renhong Zhang, Yuanyuan Zhao, Kai Li, Yaning Zhang, Mingfeng Cai, Xia Jiang, Shibo Xie, Youhua Zhou, Qiang Lu, Lu Dang, Bobo Cell Res Letter to the Editor Springer Singapore 2020-11-11 2021-01 /pmc/articles/PMC7656503/ /pubmed/33177651 http://dx.doi.org/10.1038/s41422-020-00438-w Text en © Center for Excellence in Molecular Cell Science, CAS 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
| spellingShingle | Letter to the Editor Guo, Liang Bi, Wenwen Wang, Xinling Xu, Wei Yan, Renhong Zhang, Yuanyuan Zhao, Kai Li, Yaning Zhang, Mingfeng Cai, Xia Jiang, Shibo Xie, Youhua Zhou, Qiang Lu, Lu Dang, Bobo Engineered trimeric ACE2 binds viral spike protein and locks it in “Three-up” conformation to potently inhibit SARS-CoV-2 infection |
| title | Engineered trimeric ACE2 binds viral spike protein and locks it in “Three-up” conformation to potently inhibit SARS-CoV-2 infection |
| title_full | Engineered trimeric ACE2 binds viral spike protein and locks it in “Three-up” conformation to potently inhibit SARS-CoV-2 infection |
| title_fullStr | Engineered trimeric ACE2 binds viral spike protein and locks it in “Three-up” conformation to potently inhibit SARS-CoV-2 infection |
| title_full_unstemmed | Engineered trimeric ACE2 binds viral spike protein and locks it in “Three-up” conformation to potently inhibit SARS-CoV-2 infection |
| title_short | Engineered trimeric ACE2 binds viral spike protein and locks it in “Three-up” conformation to potently inhibit SARS-CoV-2 infection |
| title_sort | engineered trimeric ace2 binds viral spike protein and locks it in “three-up” conformation to potently inhibit sars-cov-2 infection |
| topic | Letter to the Editor |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656503/ https://www.ncbi.nlm.nih.gov/pubmed/33177651 http://dx.doi.org/10.1038/s41422-020-00438-w |
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