Impact of the common MTHFR 677C→T polymorphism on blood pressure in adulthood and role of riboflavin in modifying the genetic risk of hypertension: evidence from the JINGO project

BACKGROUND: Genome-wide and clinical studies have linked the 677C→T polymorphism in the gene encoding methylenetetrahydrofolate reductase (MTHFR) with hypertension, whilst limited evidence shows that intervention with riboflavin (i.e. the MTHFR co-factor) can lower blood pressure (BP) in hypertensiv...

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Detalles Bibliográficos
Autores principales: Ward, Mary, Hughes, Catherine F., Strain, J. J., Reilly, Rosie, Cunningham, Conal, Molloy, Anne M., Horigan, Geraldine, Casey, Miriam, McCarroll, Kevin, O’Kane, Maurice, Gibney, Michael J., Flynn, Albert, Walton, Janette, McNulty, Breige A., McCann, Adrian, Kirwan, Laura, Scott, John M., McNulty, Helene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656675/
https://www.ncbi.nlm.nih.gov/pubmed/33172445
http://dx.doi.org/10.1186/s12916-020-01780-x

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