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Bioavailability of subcutaneous and intramuscular administrated buprenorphine in New Zealand White rabbits

BACKGROUND: Buprenorphine is one of the most used analgesics for postoperative pain in rabbits. The recommended dose in rabbits (0.01–0.05 mg/kg) is the same for intravenous (IV), intramuscular (IM), and subcutaneous (SC) administration, despite lack of pharmacokinetic data. Five male and five femal...

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Detalles Bibliográficos
Autores principales: Askar, Raad, Fredriksson, Elin, Manell, Elin, Hedeland, Mikael, Bondesson, Ulf, Bate, Simon, Olsén, Lena, Hedenqvist, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656698/
https://www.ncbi.nlm.nih.gov/pubmed/33176781
http://dx.doi.org/10.1186/s12917-020-02618-7