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Bone marrow mesenchymal stem cell-derived exosomes promote plasminogen activator inhibitor 1 expression in vascular cells in the local microenvironment during rabbit osteonecrosis of the femoral head
BACKGROUND: Nontraumatic osteonecrosis of the femoral head (NONFH) is a highly disabling orthopedic disease in young individuals. Plasminogen activator inhibitor 1 (PAI-1) has been reported to be positively associated with NONFH. We aimed to investigate the dysregulating PAI-1 in bone marrow mesench...
Autores principales: | Li, Lu, Wang, Yikai, Yu, Xiaobing, Bao, Yongming, An, Lijia, Wei, Xiaowei, Yu, Weiting, Liu, Baoyi, Li, Junlei, Yang, Jiahui, Xia, Yan, Liu, Ge, Cao, Fang, Zhang, Xiuzhi, Zhao, Dewei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656701/ https://www.ncbi.nlm.nih.gov/pubmed/33176873 http://dx.doi.org/10.1186/s13287-020-01991-2 |
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