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Pinocembrin ameliorates intermittent hypoxia-induced neuroinflammation through BNIP3-dependent mitophagy in a murine model of sleep apnea

BACKGROUND: Intermittent hypoxia (IH) caused by obstructive sleep apnea (OSA) leads to neuroinflammation. Pinocembrin has been shown to have neuroprotective effects, while the therapeutic functions under IH condition are still unknown. METHODS: An OSA model was established by CIH exposure inside cus...

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Detalles Bibliográficos
Autores principales:	Gong, Lin-Jing, Wang, Xin-Yuan, Gu, Wen-Yu, Wu, Xu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656728/ https://www.ncbi.nlm.nih.gov/pubmed/33176803 http://dx.doi.org/10.1186/s12974-020-02014-w

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