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Long noncoding RNA HCG18 inhibits the differentiation of human bone marrow-derived mesenchymal stem cells in osteoporosis by targeting miR-30a-5p/NOTCH1 axis

BACKGROUND: Recent studies have demonstrated that long non-coding RNAs (LncRNAs) can influence bone cell differentiation and formation. However, it is unclear whether lncRNA HCG18 is involved in osteoporosis (OP). This study was conducted to investigate the regulation of HCG18 in osteogenic differen...

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Detalles Bibliográficos
Autores principales: Che, Mingxue, Gong, Weiquan, Zhao, Yao, Liu, Mingxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656763/
https://www.ncbi.nlm.nih.gov/pubmed/33176682
http://dx.doi.org/10.1186/s10020-020-00219-6