Pharmacophore modelling of vanillin derivatives, favipiravir, chloroquine, hydroxychloroquine, monolaurin and tetrodotoxin as M(Pro) inhibitors of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)

OBJECTIVES: The aim of this study was to use Ligand-based pharmacophore modelling approach for four established antiviral drugs, namely remdesivir, lopinavir, ritonavir and hydroxychloroquine for COVID-19 inhibitors as training sets. In this study Twenty vanillin derivatives together with monolaurin...

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Detalles Bibliográficos
Autores principales: Law, Woon Yi, Asaruddin, Mohd Razip, Bhawani, Showkat Ahamd, Mohamad, Samsur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656897/
https://www.ncbi.nlm.nih.gov/pubmed/33176880
http://dx.doi.org/10.1186/s13104-020-05379-6

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