Cargando…
The Impact of the Coronavirus Disease-2019 Pandemic on the Psychological Status and Quality of Life of Myasthenia Gravis Patients
OBJECTIVES: The coronavirus disease 2019 (COVID-19) is the largest pandemic of our times. We wanted to investigate the impact of COVID-19 pandemic on the psychological status, quality of life (QoL) and quality of sleep (QoS) of myasthenia gravis (MG) patients. METHODS: Data on the epidemiological an...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7657293/ https://www.ncbi.nlm.nih.gov/pubmed/33223669 http://dx.doi.org/10.4103/aian.AIAN_551_20 |
_version_ | 1783608473337987072 |
---|---|
author | Stojanov, Aleksandar Stojanov, Jelena Milosevic, Vuk Malobabic, Marina Stanojevic, Goran Stevic, Milos Djordjevic, Gordana |
author_facet | Stojanov, Aleksandar Stojanov, Jelena Milosevic, Vuk Malobabic, Marina Stanojevic, Goran Stevic, Milos Djordjevic, Gordana |
author_sort | Stojanov, Aleksandar |
collection | PubMed |
description | OBJECTIVES: The coronavirus disease 2019 (COVID-19) is the largest pandemic of our times. We wanted to investigate the impact of COVID-19 pandemic on the psychological status, quality of life (QoL) and quality of sleep (QoS) of myasthenia gravis (MG) patients. METHODS: Data on the epidemiological and clinical characteristics of MG were collected. We used a self-designed questionnaire (consisting of 12 questions), a revised 15-item Myasthenia Gravis Quality of Life Questionnaire (MGQOL15r), a 36-item health survey of the Medical Outcomes Study Short Form (SF36), Pittsburgh sleep quality index (PSQI), Hamilton scales for the assessment of anxiety (HAM-A), and depression (HAMD) were used. We reassessed patients who were tested three years ago using the same questionnaires. RESULTS: The study included 64 MG patients. We noticed a statistically significant difference between the results obtained three years ago and the results from April 2020 in PSQI scores (P < 0.01). MGQOL15r, SF36, and PSQI scores correlate with severe clinical manifestation, high scores on HAM-A and HAM-D (P < 0.01). Higher scores on HAM-D and fear that MG symptoms will be worse if the patient gets an upper respiratory infection were independent predictors of the lower SF36 scores. Regarding MGQOL15r-independent predictors of the higher score were higher scores on HAM-D. CONCLUSIONS: There is a significant impact of the COVID-19 epidemic on the psychological status and especially on the quality of sleep of MG patients. Healthcare organizations need to provide professional therapeutic advice and psychosocial support for this population of patients during the pandemic. |
format | Online Article Text |
id | pubmed-7657293 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-76572932020-11-19 The Impact of the Coronavirus Disease-2019 Pandemic on the Psychological Status and Quality of Life of Myasthenia Gravis Patients Stojanov, Aleksandar Stojanov, Jelena Milosevic, Vuk Malobabic, Marina Stanojevic, Goran Stevic, Milos Djordjevic, Gordana Ann Indian Acad Neurol Original Article OBJECTIVES: The coronavirus disease 2019 (COVID-19) is the largest pandemic of our times. We wanted to investigate the impact of COVID-19 pandemic on the psychological status, quality of life (QoL) and quality of sleep (QoS) of myasthenia gravis (MG) patients. METHODS: Data on the epidemiological and clinical characteristics of MG were collected. We used a self-designed questionnaire (consisting of 12 questions), a revised 15-item Myasthenia Gravis Quality of Life Questionnaire (MGQOL15r), a 36-item health survey of the Medical Outcomes Study Short Form (SF36), Pittsburgh sleep quality index (PSQI), Hamilton scales for the assessment of anxiety (HAM-A), and depression (HAMD) were used. We reassessed patients who were tested three years ago using the same questionnaires. RESULTS: The study included 64 MG patients. We noticed a statistically significant difference between the results obtained three years ago and the results from April 2020 in PSQI scores (P < 0.01). MGQOL15r, SF36, and PSQI scores correlate with severe clinical manifestation, high scores on HAM-A and HAM-D (P < 0.01). Higher scores on HAM-D and fear that MG symptoms will be worse if the patient gets an upper respiratory infection were independent predictors of the lower SF36 scores. Regarding MGQOL15r-independent predictors of the higher score were higher scores on HAM-D. CONCLUSIONS: There is a significant impact of the COVID-19 epidemic on the psychological status and especially on the quality of sleep of MG patients. Healthcare organizations need to provide professional therapeutic advice and psychosocial support for this population of patients during the pandemic. Wolters Kluwer - Medknow 2020 2020-05-08 /pmc/articles/PMC7657293/ /pubmed/33223669 http://dx.doi.org/10.4103/aian.AIAN_551_20 Text en Copyright: © 2006 - 2020 Annals of Indian Academy of Neurology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Stojanov, Aleksandar Stojanov, Jelena Milosevic, Vuk Malobabic, Marina Stanojevic, Goran Stevic, Milos Djordjevic, Gordana The Impact of the Coronavirus Disease-2019 Pandemic on the Psychological Status and Quality of Life of Myasthenia Gravis Patients |
title | The Impact of the Coronavirus Disease-2019 Pandemic on the Psychological Status and Quality of Life of Myasthenia Gravis Patients |
title_full | The Impact of the Coronavirus Disease-2019 Pandemic on the Psychological Status and Quality of Life of Myasthenia Gravis Patients |
title_fullStr | The Impact of the Coronavirus Disease-2019 Pandemic on the Psychological Status and Quality of Life of Myasthenia Gravis Patients |
title_full_unstemmed | The Impact of the Coronavirus Disease-2019 Pandemic on the Psychological Status and Quality of Life of Myasthenia Gravis Patients |
title_short | The Impact of the Coronavirus Disease-2019 Pandemic on the Psychological Status and Quality of Life of Myasthenia Gravis Patients |
title_sort | impact of the coronavirus disease-2019 pandemic on the psychological status and quality of life of myasthenia gravis patients |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7657293/ https://www.ncbi.nlm.nih.gov/pubmed/33223669 http://dx.doi.org/10.4103/aian.AIAN_551_20 |
work_keys_str_mv | AT stojanovaleksandar theimpactofthecoronavirusdisease2019pandemiconthepsychologicalstatusandqualityoflifeofmyastheniagravispatients AT stojanovjelena theimpactofthecoronavirusdisease2019pandemiconthepsychologicalstatusandqualityoflifeofmyastheniagravispatients AT milosevicvuk theimpactofthecoronavirusdisease2019pandemiconthepsychologicalstatusandqualityoflifeofmyastheniagravispatients AT malobabicmarina theimpactofthecoronavirusdisease2019pandemiconthepsychologicalstatusandqualityoflifeofmyastheniagravispatients AT stanojevicgoran theimpactofthecoronavirusdisease2019pandemiconthepsychologicalstatusandqualityoflifeofmyastheniagravispatients AT stevicmilos theimpactofthecoronavirusdisease2019pandemiconthepsychologicalstatusandqualityoflifeofmyastheniagravispatients AT djordjevicgordana theimpactofthecoronavirusdisease2019pandemiconthepsychologicalstatusandqualityoflifeofmyastheniagravispatients AT stojanovaleksandar impactofthecoronavirusdisease2019pandemiconthepsychologicalstatusandqualityoflifeofmyastheniagravispatients AT stojanovjelena impactofthecoronavirusdisease2019pandemiconthepsychologicalstatusandqualityoflifeofmyastheniagravispatients AT milosevicvuk impactofthecoronavirusdisease2019pandemiconthepsychologicalstatusandqualityoflifeofmyastheniagravispatients AT malobabicmarina impactofthecoronavirusdisease2019pandemiconthepsychologicalstatusandqualityoflifeofmyastheniagravispatients AT stanojevicgoran impactofthecoronavirusdisease2019pandemiconthepsychologicalstatusandqualityoflifeofmyastheniagravispatients AT stevicmilos impactofthecoronavirusdisease2019pandemiconthepsychologicalstatusandqualityoflifeofmyastheniagravispatients AT djordjevicgordana impactofthecoronavirusdisease2019pandemiconthepsychologicalstatusandqualityoflifeofmyastheniagravispatients |