Functional analysis of a species-specific inhibitor selective for human Na(+)-coupled citrate transporter (NaCT/SLC13A5/mINDY)

The Na(+)-coupled citrate transporter (NaCT/SLC13A5/mINDY) in the liver delivers citrate from the blood into hepatocytes. As citrate is a key metabolite and regulator of multiple biochemical pathways, deletion of Slc13a5 in mice protects against diet-induced obesity, diabetes, and metabolic syndrome...

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Detalles Bibliográficos
Autores principales: Higuchi, Kei, Kopel, Jonathan J., Sivaprakasam, Sathish, Jaramillo-Martinez, Valeria, Sutton, R. Bryan, Urbatsch, Ina L., Ganapathy, Vadivel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Cell Membranes, Excitation & Transport
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7657661/
https://www.ncbi.nlm.nih.gov/pubmed/33079129
http://dx.doi.org/10.1042/BCJ20200592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7657661/
https://www.ncbi.nlm.nih.gov/pubmed/33079129
http://dx.doi.org/10.1042/BCJ20200592

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