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Blackout in the powerhouse: clinical phenotypes associated with defects in the assembly of OXPHOS complexes and the mitoribosome

Mitochondria produce the bulk of the energy used by almost all eukaryotic cells through oxidative phosphorylation (OXPHOS) which occurs on the four complexes of the respiratory chain and the F(1)–F(0) ATPase. Mitochondrial diseases are a heterogenous group of conditions affecting OXPHOS, either dire...

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Detalles Bibliográficos
Autores principales:	Hock, Daniella H., Robinson, David R. L., Stroud, David A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2020
Materias:	Bioenergetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7657662/ https://www.ncbi.nlm.nih.gov/pubmed/33151299 http://dx.doi.org/10.1042/BCJ20190767

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