Cargando…
Development of a specific troponin I detection system with enhanced immune sensitivity using a single monoclonal antibody
Using an immunoassay in combination with surface plasmon fluorescence spectroscopy (SPFS), we report the rapid detection of troponin I, a valuable biomarker for diagnosis of myocardial infarction. We discuss the implementation of (i) direct, (ii) sandwich, and (iii) competitive assay formats, based...
Autores principales: | Bozdogan, Anıl, El-Kased, Reham F., Jungbluth, Vanessa, Knoll, Wolfgang, Dostalek, Jakub, Kasry, Amal |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7657922/ https://www.ncbi.nlm.nih.gov/pubmed/33204459 http://dx.doi.org/10.1098/rsos.200871 |
Ejemplares similares
-
Monoclonal antibody stability can be usefully monitored using the excitation-energy-dependent fluorescence edge-shift
por: Knight, Michael J., et al.
Publicado: (2020) -
Ligand-induced Epitope Masking: DISSOCIATION OF INTEGRIN α5β1-FIBRONECTIN COMPLEXES ONLY BY MONOCLONAL ANTIBODIES WITH AN ALLOSTERIC MODE OF ACTION
por: Mould, A. Paul, et al.
Publicado: (2016) -
Toward Understanding the Molecular Bases of Stretch Activation: A STRUCTURAL COMPARISON OF THE TWO TROPONIN C ISOFORMS OF LETHOCERUS
por: Sanfelice, Domenico, et al.
Publicado: (2016) -
Initiating a watch list for Ebola virus antibody escape mutations
por: Miller, Craig R., et al.
Publicado: (2016) -
Highly sensitive tryptophan fluorescence probe for detecting rhythmic conformational changes of KaiC in the cyanobacterial circadian clock system
por: Mukaiyama, Atsushi, et al.
Publicado: (2022)