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Misfolded amyloid-β-42 impairs the endosomal–lysosomal pathway
Misfolding and aggregation of proteins is strongly linked to several neurodegenerative diseases, but how such species bring about their cytotoxic actions remains poorly understood. Here we used specifically-designed optical reporter probes and live fluorescence imaging in primary hippocampal neurons...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658065/ https://www.ncbi.nlm.nih.gov/pubmed/32025743 http://dx.doi.org/10.1007/s00018-020-03464-4 |