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Adjunctive Cenobamate for Focal-Onset Seizures in Adults: A Systematic Review and Meta-Analysis
BACKGROUND: Cenobamate is a novel tetrazole-derived carbamate compound with a dual mechanism of action. This drug can enhance the inactivated state of voltage-gated sodium channels, preferentially inhibiting the persistent component of the sodium channel current, and acts as a positive allosteric mo...
Autores principales: | Lattanzi, Simona, Trinka, Eugen, Zaccara, Gaetano, Striano, Pasquale, Del Giovane, Cinzia, Silvestrini, Mauro, Brigo, Francesco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658084/ https://www.ncbi.nlm.nih.gov/pubmed/32851590 http://dx.doi.org/10.1007/s40263-020-00759-9 |
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