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Population Modelling of Dexmedetomidine Pharmacokinetics and Haemodynamic Effects After Intravenous and Subcutaneous Administration

BACKGROUND AND OBJECTIVE: Dexmedetomidine is a potent agonist of α(2)-adrenoceptors causing dose-dependent sedation in humans. Intravenous dexmedetomidine is commonly used perioperatively, but an extravascular route of administration would be favoured in palliative care. Subcutaneous infusions provi...

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Detalles Bibliográficos
Autores principales:	Ashraf, Muhammad W., Uusalo, Panu, Scheinin, Mika, Saari, Teijo I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2020
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658092/ https://www.ncbi.nlm.nih.gov/pubmed/32462542 http://dx.doi.org/10.1007/s40262-020-00900-3

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