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Macrophage Regnase-1 Deletion Deteriorates Liver Ischemia/Reperfusion Injury Through Regulation of Macrophage Polarization

BACKGROUND: Regnase-1 (MCPIP) has been identified as an anti-inflammatory agent, but little is known about its influence on liver ischemia/reperfusion (I/R) injury. Macrophages can evolve biphasic responses and differentiate into remarkable polarizations, contributing greatly to the uncontrolled inf...

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Detalles Bibliográficos
Autores principales: Xiaoming, Ai, Wenbo, Jia, Jinyi, Wang, Bin, Wu, Chunyang, Hu, Qi, Chen, Lianbao, Kong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658104/
https://www.ncbi.nlm.nih.gov/pubmed/33192591
http://dx.doi.org/10.3389/fphys.2020.582347

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