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Macrophage Regnase-1 Deletion Deteriorates Liver Ischemia/Reperfusion Injury Through Regulation of Macrophage Polarization
BACKGROUND: Regnase-1 (MCPIP) has been identified as an anti-inflammatory agent, but little is known about its influence on liver ischemia/reperfusion (I/R) injury. Macrophages can evolve biphasic responses and differentiate into remarkable polarizations, contributing greatly to the uncontrolled inf...
Autores principales: | Xiaoming, Ai, Wenbo, Jia, Jinyi, Wang, Bin, Wu, Chunyang, Hu, Qi, Chen, Lianbao, Kong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658104/ https://www.ncbi.nlm.nih.gov/pubmed/33192591 http://dx.doi.org/10.3389/fphys.2020.582347 |
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