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SARS-CoV-2 receptor is co-expressed with elements of the kinin–kallikrein, renin–angiotensin and coagulation systems in alveolar cells
SARS-CoV-2, the pathogenic agent of COVID-19, employs angiotensin converting enzyme-2 (ACE2) as its cell entry receptor. Clinical data reveal that in severe COVID-19, SARS-CoV-2 infects the lung, leading to a frequently lethal triad of respiratory insufficiency, acute cardiovascular failure, and coa...
Autores principales: | Sidarta-Oliveira, Davi, Jara, Carlos Poblete, Ferruzzi, Adriano J., Skaf, Munir S., Velander, William H., Araujo, Eliana P., Velloso, Licio A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658217/ https://www.ncbi.nlm.nih.gov/pubmed/33177594 http://dx.doi.org/10.1038/s41598-020-76488-2 |
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