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Integration of metabolomics and transcriptomics reveals novel biomarkers in the blood for tuberculosis diagnosis in children
Pediatric tuberculosis (TB) remains a major global health problem. Improved pediatric diagnostics using readily available biosources are urgently needed. We used liquid chromatography-mass spectrometry to analyze plasma metabolite profiles of Indian children with active TB (n = 16) and age- and sex-...
Autores principales: | Dutta, Noton K., Tornheim, Jeffrey A., Fukutani, Kiyoshi F., Paradkar, Mandar, Tiburcio, Rafael T., Kinikar, Aarti, Valvi, Chhaya, Kulkarni, Vandana, Pradhan, Neeta, Shivakumar, Shri Vijay Bala Yogendra, Kagal, Anju, Gupte, Akshay, Gupte, Nikhil, Mave, Vidya, Gupta, Amita, Andrade, Bruno B., Karakousis, Petros C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658223/ https://www.ncbi.nlm.nih.gov/pubmed/33177551 http://dx.doi.org/10.1038/s41598-020-75513-8 |
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