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Human mesenchymal stromal/stem cells recruit resident pericytes and induce blood vessels maturation to repair experimental spinal cord injury in rats

Angiogenesis is considered to mediate the beneficial effects of mesenchymal cell therapy in spinal cord injury. After a moderate balloon-compression injury in rats, injections of either human adipose tissue-derived stromal/stem cells (hADSCs) or their conditioned culture media (CM-hADSC) elicited an...

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Detalles Bibliográficos
Autores principales: Menezes, Karla, Rosa, Barbara Gomes, Freitas, Catarina, da Cruz, Aline Silva, de Siqueira Santos, Raphael, Nascimento, Marcos Assis, Alves, Daiana Vieira Lopes, Bonamino, Martin, Rossi, Maria Isabel, Borojevic, Radovan, Coelho-Sampaio, Tatiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658254/
https://www.ncbi.nlm.nih.gov/pubmed/33177535
http://dx.doi.org/10.1038/s41598-020-76290-0