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Tumor-targeted delivery of siRNA to silence Sox2 gene expression enhances therapeutic response in hepatocellular carcinoma

RNA interference (RNAi) is one of the most promising methods for the treatment of malignant tumors. However, developing an efficient biocompatible delivery vector for small interfering RNA (siRNA) remains a challenging issue. This study aimed to prepare a non-viral tumor-targeted carrier, named RGDf...

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Detalles Bibliográficos
Autores principales: Xia, Yu, Tang, Guoyi, Chen, Yi, Wang, Changbing, Guo, Min, Xu, Tiantian, Zhao, Mingqi, Zhou, Yongjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658325/
https://www.ncbi.nlm.nih.gov/pubmed/33210026
http://dx.doi.org/10.1016/j.bioactmat.2020.10.019