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Interplay between reactive oxygen species and autophagy in the course of age-related macular degeneration
Pathological biomolecules such as lipofuscin, methylglyoxal-modified proteins (the major precursors of advanced glycationend products), misfolding protein deposits and dysfunctional mitochondria are source of oxidative stress and act as strong autophagic stimulators in age-related macular degenerati...
Autores principales: | Nita, Malgorzata, Grzybowski, Andrzej |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Leibniz Research Centre for Working Environment and Human Factors
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658465/ https://www.ncbi.nlm.nih.gov/pubmed/33192217 http://dx.doi.org/10.17179/excli2020-2915 |
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