Cargando…
Pioglitazone Ameliorates Gentamicin Ototoxicity by Affecting the TLR and STAT Pathways in the Early Postnatal Organ of Corti
Noise trauma, infection, and ototoxic drugs are frequent external causes of hearing loss. With no pharmacological treatments currently available, understanding the mechanisms and pathways leading to auditory hair cell (HC) damage and repair is crucial for identifying potential pharmacological target...
Autores principales: | Sekulic-Jablanovic, Marijana, Wright, Matthew B., Petkovic, Vesna, Bodmer, Daniel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658481/ https://www.ncbi.nlm.nih.gov/pubmed/33192313 http://dx.doi.org/10.3389/fncel.2020.566148 |
Ejemplares similares
-
Pasireotide protects mammalian cochlear hair cells from gentamicin ototoxicity by activating the PI3K–Akt pathway
por: Kucharava, Krystsina, et al.
Publicado: (2019) -
Lack of NHE6 and Inhibition of NKCC1 Associated With Increased Permeability in Blood Labyrinth Barrier-Derived Endothelial Cell Layer
por: Sekulic-Jablanovic, Marijana, et al.
Publicado: (2022) -
Geldanamycin induces production of heat shock protein 70 and partially attenuates ototoxicity caused by gentamicin in the organ of Corti explants
por: Yu, Yang, et al.
Publicado: (2009) -
STK33 alleviates gentamicin‐induced ototoxicity in cochlear hair cells and House Ear Institute‐Organ of Corti 1 cells
por: Zhou, Meijuan, et al.
Publicado: (2018) -
Human blood-labyrinth barrier model to study the effects of cytokines and inflammation
por: Sekulic, Marijana, et al.
Publicado: (2023)