Retargeted and Multi-cytokine-Armed Herpes Virus Is a Potent Cancer Endovaccine for Local and Systemic Anti-tumor Treatment

Oncolytic viruses (OVs) are novel anti-tumor agents with the ability to selectively infect and kill tumor cells while sparing normal tissue. Beyond tumor cytolysis, OVs are capable of priming an anti-tumor immune response via lysis and cross-presentation of locally expressed endogenous tumor antigen...

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Detalles Bibliográficos
Autores principales: De Lucia, Maria, Cotugno, Gabriella, Bignone, Veronica, Garzia, Irene, Nocchi, Linda, Langone, Francesca, Petrovic, Biljana, Sasso, Emanuele, Pepe, Simona, Froechlich, Guendalina, Gentile, Chiara, Zambrano, Nicola, Campadelli-Fiume, Gabriella, Nicosia, Alfredo, Scarselli, Elisa, D’Alise, Anna Morena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658578/
https://www.ncbi.nlm.nih.gov/pubmed/33209980
http://dx.doi.org/10.1016/j.omto.2020.10.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658578/
https://www.ncbi.nlm.nih.gov/pubmed/33209980
http://dx.doi.org/10.1016/j.omto.2020.10.006

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