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Dispirotripiperazine-core compounds, their biological activity with a focus on broad antiviral property, and perspectives in drug design (mini-review)

Viruses are obligate intracellular parasites and have evolved to enter the host cell. To gain access they come into contact with the host cell through an initial adhesion, and some viruses from different genus may use heparan sulfate proteoglycans for it. The successful inhibition of this early even...

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Detalles Bibliográficos
Autores principales: Egorova, Anna, Bogner, Elke, Novoselova, Elena, Zorn, Kimberley M., Ekins, Sean, Makarov, Vadim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658596/
https://www.ncbi.nlm.nih.gov/pubmed/33218683
http://dx.doi.org/10.1016/j.ejmech.2020.113014

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