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Chemoradiation impairs myofiber hypertrophic growth in a pediatric tumor model

Pediatric cancer treatment often involves chemotherapy and radiation, where off-target effects can include skeletal muscle decline. The effect of such treatments on juvenile skeletal muscle growth has yet to be investigated. We employed a small animal irradiator to administer fractionated hindlimb i...

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Detalles Bibliográficos
Autores principales: Paris, Nicole D., Kallenbach, Jacob G., Bachman, John F., Blanc, Roméo S., Johnston, Carl J., Hernady, Eric, Williams, Jacqueline P., Chakkalakal, Joe V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659015/
https://www.ncbi.nlm.nih.gov/pubmed/33177579
http://dx.doi.org/10.1038/s41598-020-75913-w