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Chimeric antigen receptor T-cell therapy in glioblastoma: charging the T cells to fight

Glioblastoma multiforme (GBM) is the most common malignant brain cancer that invades normal brain tissue and impedes surgical eradication, resulting in early local recurrence and high mortality. In addition, most therapeutic agents lack permeability across the blood brain barrier (BBB), further redu...

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Detalles Bibliográficos
Autores principales: Land, Craig A., Musich, Phillip R., Haydar, Dalia, Krenciute, Giedre, Xie, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659102/
https://www.ncbi.nlm.nih.gov/pubmed/33176788
http://dx.doi.org/10.1186/s12967-020-02598-0