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Chimeric antigen receptor T-cell therapy in glioblastoma: charging the T cells to fight
Glioblastoma multiforme (GBM) is the most common malignant brain cancer that invades normal brain tissue and impedes surgical eradication, resulting in early local recurrence and high mortality. In addition, most therapeutic agents lack permeability across the blood brain barrier (BBB), further redu...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659102/ https://www.ncbi.nlm.nih.gov/pubmed/33176788 http://dx.doi.org/10.1186/s12967-020-02598-0 |