Low Hydrophobic Mismatch Scores Calculated for HLA-A/B/DR/DQ Loci Improve Kidney Allograft Survival

We evaluated the impact of human leukocyte antigen (HLA) disparity (immunogenicity; IM) on long-term kidney allograft survival. The IM was quantified based on physicochemical properties of the polymorphic linear donor/recipient HLA amino acids (the Cambridge algorithm) as a hydrophobic, electrostati...

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Detalles Bibliográficos
Autores principales: Bekbolsynov, Dulat, Mierzejewska, Beata, Borucka, Jadwiga, Liwski, Robert S., Greenshields, Anna L., Breidenbach, Joshua, Gehring, Bradley, Leonard-Murali, Shravan, Khuder, Sadik A., Rees, Michael, Green, Robert C., Stepkowski, Stanislaw M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659444/
https://www.ncbi.nlm.nih.gov/pubmed/33193383
http://dx.doi.org/10.3389/fimmu.2020.580752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659444/
https://www.ncbi.nlm.nih.gov/pubmed/33193383
http://dx.doi.org/10.3389/fimmu.2020.580752

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