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Investigation of the Impact from IL-2, IL-7, and IL-15 on the Growth and Signaling of Activated CD4(+) T Cells

While CAR-T therapy is a growing and promising area of cancer research, it is limited by high cost and the difficulty of consistently culturing T-cells to therapeutically relevant concentrations ex-vivo. Cytokines IL-2, IL-7 and IL-15 have been found to stimulate the growth of T cells, however, the...

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Detalles Bibliográficos
Autores principales:	Coppola, Canaan, Hopkins, Brooks, Huhn, Steven, Du, Zhimei, Huang, Zuyi, Kelly, William J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659484/ https://www.ncbi.nlm.nih.gov/pubmed/33105566 http://dx.doi.org/10.3390/ijms21217814

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