CAR NK Cell Therapy for T Follicular Helper Cells

T follicular helper (T(FH)) cells are associated with the development of both autoimmune disease and T cell malignancies. In this issue, Reighard et al.,(1) describe the design of PD-L1 chimeric antigen receptor (CAR) NK cells that effectively target and eliminate T(FH) cells.

Detalles Bibliográficos
Autor principal: King, Cecile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Preview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659502/
https://www.ncbi.nlm.nih.gov/pubmed/33205057
http://dx.doi.org/10.1016/j.xcrm.2020.100009
Descripción
Sumario:T follicular helper (T(FH)) cells are associated with the development of both autoimmune disease and T cell malignancies. In this issue, Reighard et al.,(1) describe the design of PD-L1 chimeric antigen receptor (CAR) NK cells that effectively target and eliminate T(FH) cells.

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