Cargando…

CD103(+)CD8(+) T(RM) Cells Accumulate in Tumors of Anti-PD-1-Responder Lung Cancer Patients and Are Tumor-Reactive Lymphocytes Enriched with Tc17

Accumulation of CD103(+)CD8(+) resident memory T (T(RM)) cells in human lung tumors has been associated with a favorable prognosis. However, the contribution of T(RM) to anti-tumor immunity and to the response to immune checkpoint blockade has not been clearly established. Using quantitative multipl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Corgnac, Stéphanie, Malenica, Ines, Mezquita, Laura, Auclin, Edouard, Voilin, Elodie, Kacher, Jamila, Halse, Heloise, Grynszpan, Laetitia, Signolle, Nicolas, Dayris, Thibault, Leclerc, Marine, Droin, Nathalie, de Montpréville, Vincent, Mercier, Olaf, Validire, Pierre, Scoazec, Jean-Yves, Massard, Christophe, Chouaib, Salem, Planchard, David, Adam, Julien, Besse, Benjamin, Mami-Chouaib, Fathia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659589/ https://www.ncbi.nlm.nih.gov/pubmed/33205076 http://dx.doi.org/10.1016/j.xcrm.2020.100127

Ejemplares similares

Integrin-α(V)-mediated activation of TGF-β regulates anti-tumour CD8 T cell immunity and response to PD-1 blockade
por: Malenica, Ines, et al.
Publicado: (2021)

Regulation of antitumour CD8 T-cell immunity and checkpoint blockade immunotherapy by Neuropilin-1
por: Leclerc, Marine, et al.
Publicado: (2019)

Isolation of tumor-resident CD8(+) T cells from human lung tumors
por: Corgnac, Stéphanie, et al.
Publicado: (2021)

Cancer stem-like cells evade CD8(+)CD103(+) tumor-resident memory T (T(RM)) lymphocytes by initiating an epithelial-to-mesenchymal transition program in a human lung tumor model
por: Corgnac, Stéphanie, et al.
Publicado: (2022)

Human preprocalcitonin self-antigen generates TAP-dependent and -independent epitopes triggering optimised T-cell responses toward immune-escaped tumours
por: Durgeau, Aurélie, et al.
Publicado: (2018)

Recent Advances in Targeting CD8 T-Cell Immunity for More Effective Cancer Immunotherapy
por: Durgeau, Aurélie, et al.
Publicado: (2018)

The Emerging Role of CD8(+) Tissue Resident Memory T (T(RM)) Cells in Antitumor Immunity: A Unique Functional Contribution of the CD103 Integrin
por: Corgnac, Stéphanie, et al.
Publicado: (2018)

Resident memory T cells, critical components in tumor immunology
por: Mami-Chouaib, Fathia, et al.
Publicado: (2018)

Recent Advances in Lung Cancer Immunotherapy: Input of T-Cell Epitopes Associated With Impaired Peptide Processing
por: Leclerc, Marine, et al.
Publicado: (2019)

Tumor-resident memory T cells as a biomarker of the response to cancer immunotherapy
por: Damei, Isabelle, et al.
Publicado: (2023)

Mutant and non-mutant neoantigen-based cancer vaccines: recent advances and future promises
por: Ashi, Mohamad Omar, et al.
Publicado: (2022)

T-cell modulatory properties of CD5 and its role in antitumor immune responses
por: Tabbekh, Mouna, et al.
Publicado: (2013)

Predicting Immunotherapy Outcomes in Older Patients with Solid Tumors Using the LIPI Score
por: Pierro, Monica, et al.
Publicado: (2022)

When Immunity Kills: The Lessons of SARS-CoV-2 Outbreak
por: Taoufik, Yassine, et al.
Publicado: (2021)

Editorial: Tissue Resident Memory T Cells
por: Mami-Chouaib, Fathia, et al.
Publicado: (2019)

The multifaceted role of autophagy in tumor evasion from immune surveillance
por: Janji, Bassam, et al.
Publicado: (2016)

Comment on Hopkins et al. Value of the Lung Immune Prognostic Index in Patients with Non-Small Cell Lung Cancer Initiating First-Line Atezolizumab Combination Therapy: Subgroup Analysis of the IMPOWER150 Trial. Cancers 2021, 13, 1176
por: Auclin, Edouard, et al.
Publicado: (2021)

Hypoxic tumor-derived microvesicles negatively regulate NK cell function by a mechanism involving TGF-β and miR23a transfer
por: Berchem, Guy, et al.
Publicado: (2015)

Hypoxic Stress-Induced Tumor and Immune Plasticity, Suppression, and Impact on Tumor Heterogeneity
por: Terry, Stéphane, et al.
Publicado: (2017)

Targeting Autophagy in the Tumor Microenvironment: New Challenges and Opportunities for Regulating Tumor Immunity
por: Janji, Bassam, et al.
Publicado: (2018)

Tumor microenvironment-induced tumor cell plasticity: relationship with hypoxic stress and impact on tumor resistance
por: Zaarour, RF., et al.
Publicado: (2023)

Editorial: Targeting the Tumor Microenvironment for a More Effective and Efficient Cancer Immunotherapy
por: Chouaib, Salem, et al.
Publicado: (2020)

“Suffocating” tumors by blocking adaptation to hypoxia: a new headway in melanoma immunotherapy
por: Janji, Bassam, et al.
Publicado: (2021)

Vaccine Therapy in Non-Small Cell Lung Cancer
por: García-Pardo, Miguel, et al.
Publicado: (2022)

The role of hypoxia in shaping the recruitment of proangiogenic and immunosuppressive cells in the tumor microenvironment
por: Chouaib, Salem, et al.
Publicado: (2018)

Tumoral CD105 is a novel independent prognostic marker for prognosis in clear-cell renal cell carcinoma
por: Saroufim, A, et al.
Publicado: (2014)

CD8(+)PD-1(+) to CD4(+)PD-1(+) ratio (PERLS) is associated with prognosis of patients with advanced NSCLC treated with PD-(L)1 blockers
por: Duchemann, Boris, et al.
Publicado: (2022)

Apoptosis mapping in space and time of 3D tumor ecosystems reveals transmissibility of cytotoxic cancer death
por: Veith, Irina, et al.
Publicado: (2021)

Impact of Metabolism on T-Cell Differentiation and Function and Cross Talk with Tumor Microenvironment
por: Kouidhi, Soumaya, et al.
Publicado: (2017)

CXCR6 deficiency impairs cancer vaccine efficacy and CD8(+) resident memory T-cell recruitment in head and neck and lung tumors
por: Karaki, Soumaya, et al.
Publicado: (2021)

α(E)β(7) integrin interaction with E-cadherin promotes antitumor CTL activity by triggering lytic granule polarization and exocytosis
por: Floc'h, Audrey Le, et al.
Publicado: (2007)

Prognostic value of tumor mutations in radically treated locally advanced non-small cell lung cancer patients
por: Boros, Angela, et al.
Publicado: (2017)

Tumor hypoxia: an important regulator of tumor progression or a potential modulator of tumor immunogenicity?
por: Hassan Venkatesh, Goutham, et al.
Publicado: (2021)

Chronic Plasma Exposure to Kinase Inhibitors in Patients with Oncogene-Addicted Non-Small Cell Lung Cancer
por: Geraud, Arthur, et al.
Publicado: (2020)

Editorial: The intricate innate immune-cancer cell relationship in the context of tumor angiogenesis, immunity and microbiota: The angiogenic switch in the tumor microenvironment as a key target for immunotherapies
por: Mortara, Lorenzo, et al.
Publicado: (2022)

Hypoxia Promotes Tumor Growth in Linking Angiogenesis to Immune Escape
por: Chouaib, Salem, et al.
Publicado: (2012)

Intrinsic and Tumor Microenvironment-Induced Metabolism Adaptations of T Cells and Impact on Their Differentiation and Function
por: Kouidhi, Soumaya, et al.
Publicado: (2016)

Association of the Lung Immune Prognostic Index with Immunotherapy Outcomes in Mismatch Repair Deficient Tumors
por: Auclin, Edouard, et al.
Publicado: (2021)

AB008. Activated pathways of Thymic Epithelial Tumors: a RYTHMIC study
por: Benitez, Jose Carlos, et al.
Publicado: (2022)

New insights into the role of EMT in tumor immune escape
por: Terry, Stéphane, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_vu8nm356kt45ohtmr24hs6d17d