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FIT2 is an acyl–coenzyme A diphosphatase crucial for endoplasmic reticulum homeostasis
The endoplasmic reticulum is a cellular hub of lipid metabolism, coordinating lipid synthesis with continuous changes in metabolic flux. Maintaining ER lipid homeostasis despite these fluctuations is crucial to cell function and viability. Here, we identify a novel mechanism that is crucial for norm...
Autores principales: | Becuwe, Michel, Bond, Laura M., Pinto, Antonio F.M., Boland, Sebastian, Mejhert, Niklas, Elliott, Shane D., Cicconet, Marcelo, Graham, Morven M., Liu, Xinran N., Ilkayeva, Olga, Saghatelian, Alan, Walther, Tobias C., Farese, Robert V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659722/ https://www.ncbi.nlm.nih.gov/pubmed/32915949 http://dx.doi.org/10.1083/jcb.202006111 |
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