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Evaluation of acridinedione analogs as potential SARS-CoV-2 main protease inhibitors and their comparison with repurposed anti-viral drugs

BACKGROUND: The main protease (Mpro) of SARS-CoV-2 is involved in the processing of vital polypeptides required for viral genome replication and transcription and is one of the best-characterized targets to inhibit the progression of SARS-CoV-2 in infected individuals. METHODS: We screened a set of...

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Detalles Bibliográficos
Autores principales:	Bhardwaj, Vijay Kumar, Singh, Rahul, Das, Pralay, Purohit, Rituraj
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659809/ https://www.ncbi.nlm.nih.gov/pubmed/33217661 http://dx.doi.org/10.1016/j.compbiomed.2020.104117

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