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Refractory Kawasaki Disease Presenting With Erythema at Bacille Calmette-Guérin Inoculation Site: A Paediatric Case Report

Kawasaki disease (KD) is an autoimmune disease that generally affects children under the age of five years. It has a variety of clinical manifestations which may be either specific or nonspecific. Intravenous immunoglobulin and aspirin are the mainstays of treatment. There are unusual circumstances...

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Autores principales: Thadchanamoorthy, Vijayakumary, Dayasiri, Kavinda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659888/
https://www.ncbi.nlm.nih.gov/pubmed/33194494
http://dx.doi.org/10.7759/cureus.10928
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author Thadchanamoorthy, Vijayakumary
Dayasiri, Kavinda
author_facet Thadchanamoorthy, Vijayakumary
Dayasiri, Kavinda
author_sort Thadchanamoorthy, Vijayakumary
collection PubMed
description Kawasaki disease (KD) is an autoimmune disease that generally affects children under the age of five years. It has a variety of clinical manifestations which may be either specific or nonspecific. Intravenous immunoglobulin and aspirin are the mainstays of treatment. There are unusual circumstances where patients are resistant to conventional treatment. We report a one-year-old girl who presented with a 12-day history of fever in association with erythema at the site of Bacille Calmette-Guérin (BCG) scar. She did not respond successfully to conventional treatment although she was diagnosed to have Kawasaki disease. Eventually, she responded to intravenous methylprednisolone and was diagnosed as having refractory Kawasaki disease.
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spelling pubmed-76598882020-11-13 Refractory Kawasaki Disease Presenting With Erythema at Bacille Calmette-Guérin Inoculation Site: A Paediatric Case Report Thadchanamoorthy, Vijayakumary Dayasiri, Kavinda Cureus Pediatrics Kawasaki disease (KD) is an autoimmune disease that generally affects children under the age of five years. It has a variety of clinical manifestations which may be either specific or nonspecific. Intravenous immunoglobulin and aspirin are the mainstays of treatment. There are unusual circumstances where patients are resistant to conventional treatment. We report a one-year-old girl who presented with a 12-day history of fever in association with erythema at the site of Bacille Calmette-Guérin (BCG) scar. She did not respond successfully to conventional treatment although she was diagnosed to have Kawasaki disease. Eventually, she responded to intravenous methylprednisolone and was diagnosed as having refractory Kawasaki disease. Cureus 2020-10-13 /pmc/articles/PMC7659888/ /pubmed/33194494 http://dx.doi.org/10.7759/cureus.10928 Text en Copyright © 2020, Thadchanamoorthy et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pediatrics
Thadchanamoorthy, Vijayakumary
Dayasiri, Kavinda
Refractory Kawasaki Disease Presenting With Erythema at Bacille Calmette-Guérin Inoculation Site: A Paediatric Case Report
title Refractory Kawasaki Disease Presenting With Erythema at Bacille Calmette-Guérin Inoculation Site: A Paediatric Case Report
title_full Refractory Kawasaki Disease Presenting With Erythema at Bacille Calmette-Guérin Inoculation Site: A Paediatric Case Report
title_fullStr Refractory Kawasaki Disease Presenting With Erythema at Bacille Calmette-Guérin Inoculation Site: A Paediatric Case Report
title_full_unstemmed Refractory Kawasaki Disease Presenting With Erythema at Bacille Calmette-Guérin Inoculation Site: A Paediatric Case Report
title_short Refractory Kawasaki Disease Presenting With Erythema at Bacille Calmette-Guérin Inoculation Site: A Paediatric Case Report
title_sort refractory kawasaki disease presenting with erythema at bacille calmette-guérin inoculation site: a paediatric case report
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659888/
https://www.ncbi.nlm.nih.gov/pubmed/33194494
http://dx.doi.org/10.7759/cureus.10928
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