A Villin-Driven Fxr Transgene Modulates Enterohepatic Bile Acid Homeostasis and Response to an n-6-Enriched High-Fat Diet

A diet high in n-6 polyunsaturated fatty acids (PUFAs) may contribute to inflammation and tissue damage associated with obesity and pathologies of the colon and liver. One contributing factor may be dysregulation by n-6 fatty acids of enterohepatic bile acid (BA) metabolism. The farnesoid X receptor...

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Autores principales: Wren, Spencer N., Donovan, Micah G., Selmin, Ornella I., Doetschman, Tom C., Romagnolo, Donato F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659968/
https://www.ncbi.nlm.nih.gov/pubmed/33105708
http://dx.doi.org/10.3390/ijms21217829

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