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The Budesonide-Hydroxypropyl-β-Cyclodextrin Complex Attenuates ROS Generation, IL-8 Release and Cell Death Induced by Oxidant and Inflammatory Stress. Study on A549 and A-THP-1 Cells

Synthetic glucocorticoids such as budesonide (BUD) are potent anti-inflammatory drugs commonly used to treat patients suffering from chronic inflammatory diseases. A previous animal study reported a higher anti-inflammatory activity with a 2-hydroxypropyl-β-cyclodextrin (HPβCD)-based formulation of...

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Detalles Bibliográficos
Autores principales: Bayiha, Jules César, Evrard, Brigitte, Cataldo, Didier, De Tullio, Pascal, Mingeot-Leclercq, Marie-Paule
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660049/
https://www.ncbi.nlm.nih.gov/pubmed/33105741
http://dx.doi.org/10.3390/molecules25214882