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Unfortunate Outcomes in Patients With SARS-CoV-2 Superimposed on Pneumococcal Pneumonia

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the disease it causes, coronavirus disease 2019 (COVID-19), continue to have socioeconomic as well as health implications worldwide. The virus has already led to over 200,000 deaths in the United States alone. This is most likely s...

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Autores principales: Elkattawy, Sherif, Alyacoub, Ramez, Mowafy, Ahmed, Younes, Islam, Remolina, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660127/
https://www.ncbi.nlm.nih.gov/pubmed/33194501
http://dx.doi.org/10.7759/cureus.10939
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author Elkattawy, Sherif
Alyacoub, Ramez
Mowafy, Ahmed
Younes, Islam
Remolina, Carlos
author_facet Elkattawy, Sherif
Alyacoub, Ramez
Mowafy, Ahmed
Younes, Islam
Remolina, Carlos
author_sort Elkattawy, Sherif
collection PubMed
description The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the disease it causes, coronavirus disease 2019 (COVID-19), continue to have socioeconomic as well as health implications worldwide. The virus has already led to over 200,000 deaths in the United States alone. This is most likely secondary to quick respiratory deterioration seen in patients inflicted with the virus. In other words, the heightened inflammatory response leads to major organ system damage, which leads to rapid decompensation of the patient's clinical condition. Interestingly enough, some patients present with both the novel virus as well as a superimposed bacterial infection that further complicates the management of the disease. We present a case of a patient with a positive polymerase chain reaction (PCR) test for SARS-CoV-2 as well as a pneumococcal urine antigen; he was treated with both appropriate antibiotics as well as dexamethasone and remdesivir for pneumonia and novel virus, respectively. The patient's hypoxemia continued to worsen with appropriate means of oxygenation and eventually led to cardiac arrest.
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spelling pubmed-76601272020-11-13 Unfortunate Outcomes in Patients With SARS-CoV-2 Superimposed on Pneumococcal Pneumonia Elkattawy, Sherif Alyacoub, Ramez Mowafy, Ahmed Younes, Islam Remolina, Carlos Cureus Internal Medicine The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the disease it causes, coronavirus disease 2019 (COVID-19), continue to have socioeconomic as well as health implications worldwide. The virus has already led to over 200,000 deaths in the United States alone. This is most likely secondary to quick respiratory deterioration seen in patients inflicted with the virus. In other words, the heightened inflammatory response leads to major organ system damage, which leads to rapid decompensation of the patient's clinical condition. Interestingly enough, some patients present with both the novel virus as well as a superimposed bacterial infection that further complicates the management of the disease. We present a case of a patient with a positive polymerase chain reaction (PCR) test for SARS-CoV-2 as well as a pneumococcal urine antigen; he was treated with both appropriate antibiotics as well as dexamethasone and remdesivir for pneumonia and novel virus, respectively. The patient's hypoxemia continued to worsen with appropriate means of oxygenation and eventually led to cardiac arrest. Cureus 2020-10-14 /pmc/articles/PMC7660127/ /pubmed/33194501 http://dx.doi.org/10.7759/cureus.10939 Text en Copyright © 2020, Elkattawy et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Elkattawy, Sherif
Alyacoub, Ramez
Mowafy, Ahmed
Younes, Islam
Remolina, Carlos
Unfortunate Outcomes in Patients With SARS-CoV-2 Superimposed on Pneumococcal Pneumonia
title Unfortunate Outcomes in Patients With SARS-CoV-2 Superimposed on Pneumococcal Pneumonia
title_full Unfortunate Outcomes in Patients With SARS-CoV-2 Superimposed on Pneumococcal Pneumonia
title_fullStr Unfortunate Outcomes in Patients With SARS-CoV-2 Superimposed on Pneumococcal Pneumonia
title_full_unstemmed Unfortunate Outcomes in Patients With SARS-CoV-2 Superimposed on Pneumococcal Pneumonia
title_short Unfortunate Outcomes in Patients With SARS-CoV-2 Superimposed on Pneumococcal Pneumonia
title_sort unfortunate outcomes in patients with sars-cov-2 superimposed on pneumococcal pneumonia
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660127/
https://www.ncbi.nlm.nih.gov/pubmed/33194501
http://dx.doi.org/10.7759/cureus.10939
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