Cargando…
Subcellular mRNA Localization Regulates Ribosome Biogenesis in Migrating Cells
Translation of ribosomal protein-coding mRNAs (RP-mRNAs) constitutes a key step in ribosome biogenesis, but the mechanisms that modulate RP-mRNA translation in coordination with other cellular processes are poorly defined. Here, we show that subcellular localization of RP-mRNAs acts as a key regulat...
Autores principales: | Dermit, Maria, Dodel, Martin, Lee, Flora C.Y., Azman, Muhammad S., Schwenzer, Hagen, Jones, J. Louise, Blagden, Sarah P., Ule, Jernej, Mardakheh, Faraz K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660134/ https://www.ncbi.nlm.nih.gov/pubmed/33171110 http://dx.doi.org/10.1016/j.devcel.2020.10.006 |
Ejemplares similares
-
An ERK1/2‐driven RNA‐binding switch in nucleolin drives ribosome biogenesis and pancreatic tumorigenesis downstream of RAS oncogene
por: Azman, Muhammad S, et al.
Publicado: (2023) -
Methods for monitoring and measurement of protein translation in time and space
por: Dermit, Maria, et al.
Publicado: (2017) -
Purification and quantitative proteomic analysis of cell bodies and protrusions
por: Dermit, Maria, et al.
Publicado: (2021) -
Tia1 dependent regulation of mRNA subcellular location and translation controls p53 expression in B cells
por: Díaz-Muñoz, Manuel D., et al.
Publicado: (2017) -
Identifying ribosome heterogeneity using ribosome profiling
por: Alkan, Ferhat, et al.
Publicado: (2022)