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Total Synthesis of Cyclopiamide A Using Palladium-Catalyzed Domino Cyclization
Total synthesis of cyclopiamide A was accomplished using a palladium-catalyzed domino cyclization. Three rings in the tetracyclic skeleton of cyclopiamide A were constructed in a one-step domino reaction incorporating double carbopalladation and C-H activation.
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660198/ https://www.ncbi.nlm.nih.gov/pubmed/33113968 http://dx.doi.org/10.3390/molecules25214903 |
| _version_ | 1783608960790560768 |
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| author | Park, Sunhwa Shin, Kye Jung Seo, Jae Hong |
| author_facet | Park, Sunhwa Shin, Kye Jung Seo, Jae Hong |
| author_sort | Park, Sunhwa |
| collection | PubMed |
| description | Total synthesis of cyclopiamide A was accomplished using a palladium-catalyzed domino cyclization. Three rings in the tetracyclic skeleton of cyclopiamide A were constructed in a one-step domino reaction incorporating double carbopalladation and C-H activation. |
| format | Online Article Text |
| id | pubmed-7660198 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | MDPI |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-76601982020-11-13 Total Synthesis of Cyclopiamide A Using Palladium-Catalyzed Domino Cyclization Park, Sunhwa Shin, Kye Jung Seo, Jae Hong Molecules Article Total synthesis of cyclopiamide A was accomplished using a palladium-catalyzed domino cyclization. Three rings in the tetracyclic skeleton of cyclopiamide A were constructed in a one-step domino reaction incorporating double carbopalladation and C-H activation. MDPI 2020-10-23 /pmc/articles/PMC7660198/ /pubmed/33113968 http://dx.doi.org/10.3390/molecules25214903 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
| spellingShingle | Article Park, Sunhwa Shin, Kye Jung Seo, Jae Hong Total Synthesis of Cyclopiamide A Using Palladium-Catalyzed Domino Cyclization |
| title | Total Synthesis of Cyclopiamide A Using Palladium-Catalyzed Domino Cyclization |
| title_full | Total Synthesis of Cyclopiamide A Using Palladium-Catalyzed Domino Cyclization |
| title_fullStr | Total Synthesis of Cyclopiamide A Using Palladium-Catalyzed Domino Cyclization |
| title_full_unstemmed | Total Synthesis of Cyclopiamide A Using Palladium-Catalyzed Domino Cyclization |
| title_short | Total Synthesis of Cyclopiamide A Using Palladium-Catalyzed Domino Cyclization |
| title_sort | total synthesis of cyclopiamide a using palladium-catalyzed domino cyclization |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660198/ https://www.ncbi.nlm.nih.gov/pubmed/33113968 http://dx.doi.org/10.3390/molecules25214903 |
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