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Comparative genomics of Clostridioides difficile toxinotypes identifies module-based toxin gene evolution

Clostridioides difficile is a common cause of nosocomial diarrhoea. Toxins TcdA and TcdB are considered to be the main virulence factors and are encoded by the PaLoc region, while the binary toxin encoded in the CdtLoc region also contributes to pathogenicity. Variant toxinotypes reflect the genetic...

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Detalles Bibliográficos
Autores principales:	Janezic, Sandra, Dingle, Kate, Alvin, Joseph, Accetto, Tomaž, Didelot, Xavier, Crook, Derrick W., Lacy, D. Borden, Rupnik, Maja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Microbiology Society 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660249/ https://www.ncbi.nlm.nih.gov/pubmed/33030421 http://dx.doi.org/10.1099/mgen.0.000449

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